TargetMol

SKA-111

Product Code:
 
TAR-T24799
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T24799-1mg1mg£122.00
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TAR-T24799-5mg5mg£195.00
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TAR-T24799-1mL1 mL * 10 mM (in DMSO)£207.00
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TAR-T24799-10mg10mg£282.00
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TAR-T24799-25mg25mg£496.00
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TAR-T24799-50mg50mg£686.00
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TAR-T24799-100mg100mg£930.00
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TAR-T24799-500mg500mg£1,797.00
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Further Information

Bioactivity:
SKA-111 is a positive KCa channel gating modulator. It also has selectivity for KCa3.1.
CAS:
1369170-24-0
Formula:
C12H10N2S
Molecular Weight:
214.29
Pathway:
Membrane transporter/Ion channel
Purity:
0.98
SMILES:
Cc1cc2sc(N)nc2c2ccccc12
Target:
Potassium Channel

References

1. Oliv?n-Viguera A, Valero MS, Pinilla E, Amor S, Garc?a-Villal?n ?L, Coleman N, Lar?a C, Calv?n-Tienza V, Garc?a-Ot?n ?L, Fern?ndez-Fern?ndez JM, Murillo MD, G?lvez JA, D?az-de-Villegas MD, Badorrey R, Simonsen U, Rivera L, Wulff H, K?hler R. Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed. Basic Clin Pharmacol Toxicol. 2016 Aug;119(2):184-92. doi: 10.1111/bcpt.12560. Epub 2016 Feb 29. PubMed PMID: 26821335; PubMed Central PMCID: PMC5720859. 2. Coleman N, Brown BM, Oliv?n-Viguera A, Singh V, Olmstead MM, Valero MS, K?hler R, Wulff H. New positive Ca2+-activated K+ channel gating modulators with selectivity for KCa3.1. Mol Pharmacol. 2014 Sep;86(3):342-57. doi: 10.1124/mol.114.093286. Epub 2014 Jun 23. PubMed PMID: 24958817; PubMed Central PMCID: PMC4152908.