TargetMol

RETRA

Product Code:
 
TAR-T24709
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24709-5mg5mg£850.00
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Quantity:
TAR-T24709-50mg50mg£1,661.00
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Quantity:
TAR-T24709-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
RETRA is an agent of anticancer that acts by exerting anticancer activity in Ewing's sarcoma cells independent of their TP53 status.
CAS:
1035875-01-4
Formula:
C11H12BrNO3S2
Molecular Weight:
350.25
Purity:
0.98
SMILES:
Br.Oc1ccc(cc1O)C(=O)CSC1=NCCS1

References

1. Retra K, deWalick S, Schmitz M, Yazdanbakhsh M, Tielens AG, Brouwers JF, van Hellemond JJ. The tegumental surface membranes of Schistosoma mansoni are enriched in parasite-specific phospholipid species. Int J Parasitol. 2015 Aug;45(9-10):629-36. doi: 10.1016/j.ijpara.2015.03.011. Epub 2015 May 11. PubMed PMID: 25975668. 2. Sonnemann J, Grauel D, Bl?mel L, Hentschel J, Marx C, Blumrich A, Focke K, Becker S, Wittig S, Schinkel S, Kr?mer OH, Beck JF. RETRA exerts anticancer activity in Ewing's sarcoma cells independent of their TP53 status. Eur J Cancer. 2015 May;51(7):841-51. doi: 10.1016/j.ejca.2015.02.016. Epub 2015 Mar 19. PubMed PMID: 25801700. 3. Santag S, J?ger W, Karsten CB, Kati S, Pietrek M, Steinemann D, Sarek G, Ojala PM, Schulz TF. Recruitment of the tumour suppressor protein p73 by Kaposi's Sarcoma Herpesvirus latent nuclear antigen contributes to the survival of primary effusion lymphoma cells. Oncogene. 2013 Aug 8;32(32):3676-85. doi: 10.1038/onc.2012.385. Epub 2012 Sep 10. PubMed PMID: 22964633. 4. Edink E, Rucktooa P, Retra K, Akdemir A, Nahar T, Zuiderveld O, van Elk R, Janssen E, van Nierop P, van Muijlwijk-Koezen J, Smit AB, Sixma TK, Leurs R, de Esch IJ. Fragment growing induces conformational changes in acetylcholine-binding protein: a structural and thermodynamic analysis. J Am Chem Soc. 2011 Apr 13;133(14):5363-71. doi: 10.1021/ja110571r. Epub 2011 Feb 15. PubMed PMID: 21322593.