TargetMol

PA-9

Product Code:
 
TAR-T24585
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24585-5mg5mg£458.00
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Quantity:
TAR-T24585-50mg50mg£1,661.00
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Quantity:
TAR-T24585-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
PA-9 is the first small-molecule PAC1 receptor antagonist.
CAS:
1436004-46-4
Formula:
C17H18N6O2
Molecular Weight:
338.371
Purity:
0.98
SMILES:
O=C(NCCc1c[nH]cn1)C1CN(C(=O)C1)c1n[nH]c2ccccc12

References

1. Takasaki I, Watanabe A, Yokai M, Watanabe Y, Hayakawa D, Nagashima R, Fukuchi M, Okada T, Toyooka N, Miyata A, Gouda H, Kurihara T. In silico screening identified novel small-molecule antagonists of PAC1 receptor. J Pharmacol Exp Ther. 2018 Jan 23. pii: jpet.117.245415. doi: 10.1124/jpet.117.245415. [Epub ahead of print] PubMed PMID: 29363578. 2. Maslennikova IL, Kuznetsova MV, Nekrasova IV, Shirshev SV. Effect of bacterial components of mixed culture supernatants of planktonic and biofilm Pseudomonas aeruginosa with commensal Escherichia coli on the neutrophil response in vitro. Pathog Dis. 2017 Nov 30;75(8). doi: 10.1093/femspd/ftx105. PubMed PMID: 28961860. 3. Demmelmaier I, Bj?rk A, Dufour AB, Nordgren B, Opava CH. Trajectories of fear-avoidance beliefs on physcial activity over two years in people with rheumatoid arthritis. Arthritis Care Res (Hoboken). 2017 Sep 21. doi: 10.1002/acr.23419. [Epub ahead of print] PubMed PMID: 28941003. 4. Dwyer KM, Clark CJ, MacDonald K, Paraskeva MA, Rogers N, Ryan J, Webster AC, Wong G. Gender Equity in Transplantation: A Report from the Women in Transplantation Workshop of The Transplantation Society of Australia and New Zealand. Transplantation. 2017 Oct;101(10):2266-2270. doi: 10.1097/TP.0000000000001900. PubMed PMID: 28767533.