TargetMol

PFK-015

Product Code:
 
TAR-T2455
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2455-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T2455-5mg5mg£112.00
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TAR-T2455-10mg10mg£136.00
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TAR-T2455-25mg25mg£201.00
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TAR-T2455-50mg50mg£309.00
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TAR-T2455-100mg100mg£425.00
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TAR-T2455-200mg200mg£562.00
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TAR-T2455-500mg500mg£854.00
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This product comes from: United States.
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Further Information

Bioactivity:
PFK-015 is an effective inhibitor of PFKFB3 (IC50: 110 nM) and inhibits PFKFB3 activity in Y cells (IC50: 20 nM).
CAS:
4382-63-2
Formula:
C17H12N2O
Molecular Weight:
260.296
Pathway:
Metabolism; Autophagy
Purity:
0.997
SMILES:
O=C(C=Cc1ccc2ccccc2n1)c1ccncc1
Target:
Glucokinase; Autophagy

References

1. Clem BF, et al. Mol Cancer Ther. 2013, 12(8), 1461-1470. 2. Zhang Y, Wang X, Li X, et al. Synergistic effect of colistin combined with PFK-158 against colistin-resistant Enterobacteriaceae[J]. Antimicrobial agents and chemotherapy. 2019, 63(7): e00271-19.