TargetMol

Kurasoin B

Product Code:
 
TAR-T24273
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T24273-5mg5mg£850.00
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TAR-T24273-50mg50mg£1,661.00
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Quantity:
TAR-T24273-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Kurasoin B is an inhibitor of protein farnesyltransferase.
CAS:
193696-42-3
Formula:
C18H17NO2
Molecular Weight:
279.339
Purity:
0.98
SMILES:
O[C@H](Cc1c[nH]c2ccccc12)C(=O)Cc1ccccc1

References

1. Lin Z, Marett L, Hughen RW, Flores M, Forteza I, Ammon MA, Concepcion GP, Espino S, Olivera BM, Rosenberg G, Haygood MG, Light AR, Schmidt EW. Neuroactive diol and acyloin metabolites from cone snail-associated bacteria. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4867-9. doi: 10.1016/j.bmcl.2013.06.088. Epub 2013 Jul 8. PubMed PMID: 23880542; PubMed Central PMCID: PMC3779075. 2. Andrus MB, Hicken EJ, Stephens JC, Bedke DK. Total synthesis of the hydroxyketone kurasoin A using asymmetric phase-transfer alkylation. J Org Chem. 2006 Oct 27;71(22):8651-4. PubMed PMID: 17064051. 3. Sunazuka T, Hirose T, Tian ZM, Uchida R, Shiomi K, Harigaya Y, Omura S. Syntheses and absolute structures of novel protein farnesyltransferase inhibitors, kurasoins A and B. J Antibiot (Tokyo). 1997 May;50(5):453-5. PubMed PMID: 9207919. 4. Uchida R, Shiomi K, Inokoshi J, Masuma R, Kawakubo T, Tanaka H, Iwai Y, Omura S. Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities. J Antibiot (Tokyo). 1996 Sep;49(9):932-4. PubMed PMID: 8931728.