TargetMol

JTT-010

Product Code:
 
TAR-T24224
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T24224-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24224-50mg50mg£1,821.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24224-100mg100mg£2,319.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
JTT-010 is a selective inhibitor of protein kinase C-beta isoform.
CAS:
872422-30-5
Formula:
C23H23N3O5S
Molecular Weight:
453.51
Purity:
0.98
SMILES:
CS(O)(=O)=O.NC[C@H]1Cc2c(C3=C(C(=O)NC3=O)c3ccccc3)c3ccccc3n2C1

References

1. Sasase T, Morinaga H, Abe T, Miyajima K, Ohta T, Shinohara M, Matsushita M, Kakehashi A. Protein kinase C beta inhibitor prevents diabetic peripheral neuropathy, but not histopathological abnormalities of retina in Spontaneously Diabetic Torii rat. Diabetes Obes Metab. 2009 Nov;11(11):1084-7. doi: 10.1111/j.1463-1326.2009.01082.x. Epub 2009 Jul 13. PubMed PMID: 19614949. 2. Tanaka M, Ubukata M, Matsuo T, Yasue K, Matsumoto K, Kajimoto Y, Ogo T, Inaba T. One-step synthesis of heteroaromatic-fused pyrrolidines via cyclopropane ring-opening reaction: application to the PKCbeta inhibitor JTT-010. Org Lett. 2007 Aug 16;9(17):3331-4. Epub 2007 Jul 26. PubMed PMID: 17655251. 3. Sasase T, Yamada H, Sakoda K, Imagawa N, Abe T, Ito M, Sagawa S, Tanaka M, Matsushita M. Novel protein kinase C-beta isoform selective inhibitor JTT-010 ameliorates both hyper- and hypoalgesia in streptozotocin- induced diabetic rats. Diabetes Obes Metab. 2005 Sep;7(5):586-94. PubMed PMID: 16050952.