TargetMol

IMM-H004

Product Code:
 
TAR-T24161
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T24161-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24161-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T24161-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
IMM-H004 is an effective inhibitor of BV2 microglia activation.
CAS:
1456807-80-9
Formula:
C16H20N2O4
Molecular Weight:
304.346
Purity:
0.98
SMILES:
COc1cc(O)cc2oc(=O)c(N3CCN(C)CC3)c(C)c12

References

1. Jiang J, Zhang Z, Zou X, Wang R, Bai J, Zhao S, Fan X, Sheng L, Li Y. Determination of IMM-H004 and its active glucuronide metabolite in rat plasma and Ringer's solution by ultra-performance liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Feb 1;1074-1075:16-24. doi: 10.1016/j.jchromb.2017.12.030. Epub 2017 Dec 29. PubMed PMID: 29329091. 2. Knecht T, Story J, Liu J, Davis W, Borlongan CV, Dela Pe?a IC. Adjunctive Therapy Approaches for Ischemic Stroke: Innovations to Expand Time Window of Treatment. Int J Mol Sci. 2017 Dec 19;18(12). pii: E2756. doi: 10.3390/ijms18122756. Review. PubMed PMID: 29257093; PubMed Central PMCID: PMC5751355. 3. Niu F, Song XY, Hu JF, Zuo W, Kong LL, Wang XF, Han N, Chen NH. IMM-H004, A New Coumarin Derivative, Improved Focal Cerebral Ischemia via Blood-Brain Barrier Protection in Rats. J Stroke Cerebrovasc Dis. 2017 Oct;26(10):2065-2073. doi: 10.1016/j.jstrokecerebrovasdis.2016.11.121. Epub 2017 Jun 29. PubMed PMID: 28669655. 4. Zhang Z, Wu X, Zhao M, Yang Y, Wang Y, Hu J, Wang B, Sheng L, Li Y. Determination of IMM-H004, a novel neuroprotective agent, in rat plasma and brain tissue by liquid chromatography-tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Mar 24;1048:49-55. doi: 10.1016/j.jchromb.2017.02.005. Epub 2017 Feb 6. PubMed PMID: 28213295.