TargetMol

DJ101

Product Code:
 
TAR-T24005
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T24005-5mg5mg£850.00
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Quantity:
TAR-T24005-50mg50mg£1,661.00
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Quantity:
TAR-T24005-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DJ101is an effective and metabolically stable inhibitor of tubulin. It can circumvent the drug efflux pumps responsible for multidrug resistance of existing tubulin inhibitors.
CAS:
1803242-21-8
Formula:
C23H20N4O3
Molecular Weight:
400.438
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1OC)-c1nccc2[nH]c(nc12)-c1cccc2[nH]ccc12

References

1. Arnst KE, Wang Y, Hwang DJ, Xue Y, Costello T, Hamilton D, Chen Q, Yang J, Park F, Dalton JT, Miller DD, Li W. A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance. Cancer Res. 2018 Jan 1;78(1):265-277. doi: 10.1158/0008-5472.CAN-17-0577. Epub 2017 Nov 27. PubMed PMID: 29180476.