TargetMol

Dacopafant

Product Code:
 
TAR-T23951
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T23951-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23951-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23951-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Dacopafant is an antagonist of platlet activationg factor receptor.
CAS:
125372-33-0
Formula:
C12H11N3OS
Molecular Weight:
245.3
Purity:
0.98
SMILES:
NC(=O)c1ccn2[C@H](SCc12)c1cccnc1

References

1. Serradji N, Bensaid O, Martin M, Kan E, Dereuddre-Bosquet N, Redeuilh C, Huet J, Heymans F, Lamouri A, Clayette P, Dong CZ, Dormont D, Godfroid JJ. Structure-activity relationships in platelet-activating factor (PAF). 10. From PAF antagonism to inhibition of HIV-1 replication. J Med Chem. 2000 Jun 1;43(11):2149-54. PubMed PMID: 10841793. 2. Clayette P, Dereuddre-Bosquet N, Martin M, Fretier P, Dormont D. Effects of RP 55778, a tumor necrosis factor alpha synthesis inhibitor, on antiviral activity of dideoxynucleosides. Antimicrob Agents Chemother. 1997 Apr;41(4):875-7. PubMed PMID: 9087512; PubMed Central PMCID: PMC163817. 3. Renesto P, Vicart P, Paulin D, Chignard M. Protective effect of platelet activating factor antagonists on cultured endothelial cell lysis induced by elastase or activated neutrophils. Br J Pharmacol. 1996 Mar;117(5):902-6. PubMed PMID: 8851508; PubMed Central PMCID: PMC1909414. 4. van Rossem K, Vermari?n H, Decuyper K, Bourgain R. The role of PAF and the effect of a specific PAF antagonist on local tissue PO2 and neuronal integrity during and after photothrombotic brain infarction in unanesthetised rabbits. Adv Exp Med Biol. 1996;388:423-9. PubMed PMID: 8798843.