TargetMol

AHR-5333

Product Code:
 
TAR-T23683
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23683-5mg5mg£850.00
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TAR-T23683-50mg50mg£1,661.00
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Quantity:
TAR-T23683-100mg100mg£2,079.00
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This product comes from: United States.
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  • Further Information
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Further Information

Bioactivity:
AHR-5333 an antiallergy agent.
CAS:
60284-71-1
Formula:
C30H33F2NO4
Molecular Weight:
509.594
Purity:
0.98
SMILES:
COc1cc(ccc1OCCCN1CCC(CC1)C(O)(c1ccc(F)cc1)c1ccc(F)cc1)C(C)=O

References

1. v1: Greene SV, Krebs HA, Lemieux RE, Cheng LK. Determination of a new anti-allergenic agent, 1-[4-[3-[4-[bis-(4-fluorophenyl)hydroxymethyl]-1-piperidinyl] propoxy]-3-methoxyphenyl]ethanone, and its active acidic metabolite in plasma by high-performance liquid chromatography. J Chromatogr. 1990 May 18;527(2):397-405. PubMed PMID: 2387886. 2. Graff G, Anderson LA. 1-[4-[3-[4-[bis(4-fluorophenyl)hydroxymethyl]-1- piperidinyl]propoxy]-3-methoxyphenyl]ethanone(AHR-5333): a selective human blood neutrophil 5-lipoxygenase inhibitor. Prostaglandins. 1989 Oct;38(4):473-96. PubMed PMID: 2554366. 3. Walsh DA, Franzyshen SK, Yanni JM. Synthesis and antiallergy activity of 4-(diarylhydroxymethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds. J Med Chem. 1989 Jan;32(1):105-18. PubMed PMID: 2562852. 4. Yanni JM, Halliwell RE, Tracy CH. Effect of AHR-5333 on flea antigen extract-induced skin reactions in flea-allergic dogs. J Vet Pharmacol Ther. 1988 Jun;11(2):221-5. PubMed PMID: 3184263.