TargetMol

SMER3

Product Code:
 
TAR-T23371
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23371-5mg5mg£112.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23371-1mL1 mL * 10 mM (in DMSO)£117.00
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Quantity:
TAR-T23371-10mg10mg£142.00
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Quantity:
TAR-T23371-25mg25mg£213.00
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Quantity:
TAR-T23371-50mg50mg£289.00
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Quantity:
TAR-T23371-100mg100mg£389.00
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Quantity:
TAR-T23371-500mg500mg£822.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SMER 3 is an inhibitor of the Skp1-Cullin-F-box (SCF)(Met30) ubiquitin ligase, a member of the SCF E3-ligase family, which regulates diverse cellular processes including transcription, cell-cycle control and immune response.
CAS:
67200-34-4
Formula:
C11H4N4O2
Molecular Weight:
224.18
Pathway:
Others|PROTAC
Purity:
0.9835
SMILES:
O=C1C2=CC=CC=C2C3=NC4=NON=C4N=C31
Target:
Others|Ligand for E3 Ligase

References

1. Boscaro C, et al. Non-genomic mechanisms in the estrogen regulation of glycolytic protein levels in endothelial cells. FASEB J. 2020 Sep;34(9):12768-12784. 2. Mariam Aghajan, et al. Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase. Nat Biotechnol. 2010 Jul;28(7):738-42.