TargetMol

SAR407899 hydrochloride

Product Code:
 
TAR-T23308
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23308-5mg5mg£108.00
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TAR-T23308-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T23308-10mg10mg£128.00
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TAR-T23308-25mg25mg£173.00
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TAR-T23308-50mg50mg£249.00
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TAR-T23308-100mg100mg£356.00
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TAR-T23308-500mg500mg£747.00
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Further Information

Bioactivity:
SAR407899 hydrochloride is a selective, potent and ATP-competitive ROCK inhibitor, with an IC50 of 135 nM for ROCK-2, and Kis of 36 nM and 41 nM for human and rat ROCK-2, respectively.
CAS:
923262-96-8
Formula:
C14H17ClN2O2
Molecular Weight:
280.75
Pathway:
Cytoskeletal Signaling; Cell Cycle/Checkpoint; Stem Cells
Purity:
0.9801
SMILES:
Cl.O=c1[nH]ccc2cc(OC3CCNCC3)ccc12
Target:
ROCK

References

1. Matthias L?hn, et al. Pharmacological characterization of SAR407899, a novel rho-kinase inhibitor. Hypertension. 2009 Sep;54(3):676-83.