TargetMol

Icotinib Hydrochloride

Product Code:
 
TAR-T2307
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T2307-5mg5mg£116.00
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TAR-T2307-1mL1 mL * 10 mM (in DMSO)£121.00
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TAR-T2307-10mg10mg£136.00
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TAR-T2307-25mg25mg£189.00
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TAR-T2307-50mg50mg£264.00
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TAR-T2307-100mg100mg£361.00
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Quantity:
TAR-T2307-200mg200mg£510.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of EGFR, with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types.
CAS:
1204313-51-8
Formula:
C22H22ClN3O4
Molecular Weight:
427.89
Pathway:
Tyrosine Kinase/Adaptors; JAK/STAT signaling; Angiogenesis
Purity:
0.9977
SMILES:
Cl.C#Cc1cccc(Nc2ncnc3cc4OCCOCCOCCOc4cc23)c1
Target:
EGFR

References

1. Tan F, et al. Lung Y. 2012 May;76(2):177-82.