TargetMol

MM 11253

Product Code:
 
TAR-T23005
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T23005-1mg1mg£98.00
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TAR-T23005-5mg5mg£135.00
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TAR-T23005-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T23005-10mg10mg£173.00
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TAR-T23005-25mg25mg£303.00
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TAR-T23005-50mg50mg£436.00
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Quantity:
TAR-T23005-100mg100mg£610.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MM 11253 is a RARγ antagonist with IC50 of 44nM.
CAS:
345952-44-5
Formula:
C28H30O2S2
Molecular Weight:
462.67
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O
Target:
Retinoid Receptor

References

1. M I Dawson, et al. Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced ornithine decarboxylase (ODC) activity by retinoids: a potential role for trans-RA-induced ZBP-89 in ODC inhibition. Int J Cancer. 2001 Jan 1;91(1):8-21. 2. Q Le, et al. Modulation of retinoic acid receptor function alters the growth inhibitory response of oral SCC cells to retinoids. Oncogene. 2000 Mar 9;19(11):1457-65.