TargetMol

ER 50891

Product Code:
 
TAR-T22767
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22767-1mg1mg£229.00
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TAR-T22767-5mg5mg£465.00
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TAR-T22767-10mg10mg£535.00
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TAR-T22767-25mg25mg£815.00
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Quantity:
TAR-T22767-50mg50mg£1,083.00
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Quantity:
TAR-T22767-100mg100mg£1,420.00
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Quantity:
TAR-T22767-500mg500mg£2,793.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
RARα receptor antagonist
CAS:
187400-85-7
Formula:
C29H24N2O2
Molecular Weight:
432.523
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)c1cccc2c(cc(nc12)-c1ccc([nH]1)-c1ccc(cc1)C(O)=O)-c1ccccc1
Target:
Retinoid Receptor

References

Batran RZ, et al. New quinolone derivatives as neuropeptide S receptor antagonists: Design, synthesis, homology modeling, dynamic simulations and modulation of Gq/Gs signaling pathways. Bioorg Chem. 2021;111:104817. Sun W, et al. All-trans retinoic acid and human salivary histatin-1 promote the spreading and osteogenic activities of pre-osteoblasts in vitro. FEBS Open Bio. 2020;10(3):396-406. Wang S, et al. The Antagonist of Retinoic Acid Receptor ?, ER-50891 Antagonizes the Inhibitive Effect of All-Trans Retinoic Acid and Rescues Bone Morphogenetic Protein 2-Induced Osteoblastogenic Differentiation. Drug Des Devel Ther. 2020;14:297-308. Kyzer JL, et al. Investigation of selective retinoic acid receptor alpha antagonist ER-50891 and related analogs for male contraception [published online ahead of print, 2023 May 8]. Arch Pharm (Weinheim). 2023;e2300031.