TargetMol

JX06

Product Code:
 
TAR-T22350
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22350-5mg5mg£105.00
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Quantity:
TAR-T22350-1mL1 mL * 10 mM (in DMSO)£109.00
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TAR-T22350-10mg10mg£127.00
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Quantity:
TAR-T22350-25mg25mg£201.00
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Quantity:
TAR-T22350-50mg50mg£289.00
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Quantity:
TAR-T22350-100mg100mg£436.00
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This product comes from: United States.
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Further Information

Bioactivity:
JX06, a potent, selective and covalent PDK inhibitor, inhibits PDK1, PDK2 and PDK3 with IC50 of 49 nM, 101 nM and 313 nM respectively.
CAS:
729-46-4
Formula:
C10H16N2O2S4
Molecular Weight:
324.49
Pathway:
Metabolism; PI3K/Akt/mTOR signaling; Apoptosis
Purity:
0.9966
SMILES:
S=C(SSC(=S)N1CCOCC1)N1CCOCC1
Target:
Apoptosis; Dehydrogenase; PDK

References

1. Sun W , Xie Z , Liu Y , et al. JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification[J]. Cancer Research, 2015:4923-4936.