TargetMol

Lochnerine

Product Code:
 
TAR-T20801
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T20801-5mg5mg£1,396.00
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Further Information

Bioactivity:
Lochnerine is an alkaloid of terpenoid indole.
CAS:
522-47-4
Formula:
C20H24N2O2
Molecular Weight:
324.424
Purity:
0.98
SMILES:
COc1ccc2[nH]c3[C@@H]4C[C@H]5[C@@H](CO)[C@H](Cc3c2c1)N4CC5=CC

References

1. Edwankar CR, Edwankar RV, Namjoshi OA, Liao X, Cook JM. Stereospecific approach to the synthesis of ring-A oxygenated sarpagine indole alkaloids. Total synthesis of the dimeric indole alkaloid P-(+)-dispegatrine and six other monomeric indole alkaloids. J Org Chem. 2013 Jul 5;78(13):6471-87. doi: 10.1021/jo400469t. Epub 2013 Jun 18. PubMed PMID: 23721107; PubMed Central PMCID: PMC3722876. 2. Wang L, Zhang Y, He HP, Zhang Q, Li SF, Hao XJ. Three new terpenoid indole alkaloids from Catharanthus roseus. Planta Med. 2011 May;77(7):754-8. doi: 10.1055/s-0030-1250569. Epub 2010 Nov 23. PubMed PMID: 21104604. 3. Inaba M, Nagashima K. Non-antitumor vinca alkaloids reverse multidrug resistance in P388 leukemia cells in vitro. Jpn J Cancer Res. 1986 Feb;77(2):197-204. PubMed PMID: 3082832. 4. Zaima K, Koga I, Iwasawa N, Hosoya T, Hirasawa Y, Kaneda T, Ismail IS, Lajis NH, Morita H. Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma. J Nat Med. 2013 Jan;67(1):9-16. doi: 10.1007/s11418-012-0638-y. Epub 2012 Feb 21. PubMed PMID: 22350216.