TargetMol

Clemastine

Product Code:
 
TAR-T19966
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19966-1mL1 mL * 10 mM (in DMSO)£118.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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TAR-T19966-10mg10mg£119.00
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TAR-T19966-25mg25mg£149.00
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TAR-T19966-50mg50mg£197.00
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Quantity:
TAR-T19966-100mg100mg£259.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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  • Further Information
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Further Information

Bioactivity:
Clemastine has been found to rescue impaired myelination and reverse social avoidance behavior in mice.
CAS:
15686-51-8
Formula:
C21H26ClNO
Molecular Weight:
343.9
Pathway:
Immunology/Inflammation|Neuroscience|GPCR/G Protein
Purity:
0.98
SMILES:
CN1CCC[C@@H]1CCO[C@](C)(c1ccccc1)c1ccc(Cl)cc1
Target:
Histamine Receptor

References

1. Turski CA, Turski GN, Chen B, Wang H, Heidari M, Li L, Noguchi KK, Westmark C, Duncan I, Ikonomidou C. Clemastine effects in rat models of a myelination disorder. Pediatr Res. 2018 May 2. doi: 10.1038/pr.2018.45. [Epub ahead of print] PubMed PMID: 29584714. 2. Domaga?a A, Szepietowski J, Reich A. Antihistamines in the treatment of pruritus in psoriasis. Postepy Dermatol Alergol. 2017 Oct;34(5):457-463. doi: 10.5114/ada.2017.71112. Epub 2017 Oct 31. PubMed PMID: 29507561; PubMed Central PMCID: PMC5831281. 3. Magno Pereira V, Andrade C, Figueira R, Faria G, Jasmins L. Infliximab-Induced Lupus: A Case Report. GE Port J Gastroenterol. 2017 Mar;24(2):84-88. doi: 10.1159/000450877. Epub 2016 Nov 19. PubMed PMID: 29255743; PubMed Central PMCID: PMC5729968. 4. Cree BAC, Niu J, Hoi KK, Zhao C, Caganap SD, Henry RG, Dao DQ, Zollinger DR, Mei F, Shen YA, Franklin RJM, Ullian EM, Xiao L, Chan JR, Fancy SPJ. Clemastine rescues myelination defects and promotes functional recovery in hypoxic brain injury. Brain. 2018 Jan 1;141(1):85-98. doi: 10.1093/brain/awx312. PubMed PMID: 29244098.