TargetMol

TCPOBOP

Product Code:
 
TAR-T17018
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17018-5mg5mg£107.00
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TAR-T17018-10mg10mg£125.00
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TAR-T17018-25mg25mg£172.00
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TAR-T17018-50mg50mg£237.00
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TAR-T17018-100mg100mg£334.00
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Quantity:
TAR-T17018-200mg200mg£466.00
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This product comes from: United States.
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Further Information

Bioactivity:
TCPOBOP is a constitutive androstane receptor agonist that induces robust hepatocyte proliferation and hepatomegaly. TCPOBOP decreases Fas-induced murine liver injury by altering Bcl-2 proteins.
CAS:
76150-91-9
Formula:
C16H8Cl4N2O2
Molecular Weight:
402.05
Pathway:
Apoptosis
Purity:
0.9808
SMILES:
Clc1cnc(Oc2ccc(Oc3ncc(Cl)cc3Cl)cc2)c(Cl)c1
Target:
BCL

References

1. Bhushan B, et al. TCPOBOP-Induced Hepatomegaly and Hepatocyte Proliferation are Attenuated by Combined Disruption of MET and EGFR Signaling. Hepatology. 2019 Apr;69(4):1702-1718. 2. Baskin-Bey ES, et al. Constitutive androstane receptor (CAR) ligand, TCPOBOP, attenuates Fas-induced murine liver injury by altering Bcl-2 proteins. Hepatology. 2006 Jul;44(1):252-62.