TargetMol

Tarafenacin

Product Code:
 
TAR-T16990
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16990-5mg5mg£850.00
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TAR-T16990-50mg50mg£1,661.00
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Quantity:
TAR-T16990-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tarafenacin is a highly selective M3 muscarinic receptor antagonist (Ki= 0.19 nM), ~200 fold selectivity over the M2 receptor.
CAS:
385367-47-5
Formula:
C21H20F4N2O2
Molecular Weight:
408.397
Purity:
0.98
SMILES:
Fc1cccc(c1)N(Cc1cc(F)c(F)c(F)c1)C(=O)O[C@H]1CN2CCC1CC2

References

1. Salcedo C, et al. In vivo and in vitro pharmacological characterization of SVT-40776, a novel M3 muscarinic receptor antagonist, for the treatment of overactive bladder. Br J Pharmacol. 2009 Mar;156(5):807-17. 2. Huang X, et al. Microscopic binding of M5 muscarinic acetylcholine receptor with antagonists by homology modeling, molecular docking, and molecular dynamics simulation. J Phys Chem B. 2012 Jan 12;116(1):532-41.