TargetMol

Sauristolactam

Product Code:
 
TAR-T16846
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16846-5mg5mg£850.00
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Further Information

Bioactivity:
Sauristolactam inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation. Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus Chinensis. Sauristolactam has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells.
CAS:
128533-02-8
Formula:
C17H13NO3
Molecular Weight:
279.295
Purity:
0.98
SMILES:
COc1c(O)cc2C(=O)N(C)c3cc4ccccc4c1c23

References

1. Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6. 2. Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72(3):719-26.