TargetMol

Ro 363

Product Code:
 
TAR-T16769
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16769-5mg5mg£850.00
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TAR-T16769-50mg50mg£1,661.00
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TAR-T16769-100mg100mg£2,079.00
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Further Information

Bioactivity:
RO 363 is an effective inotropic stimulant and is a cardiovascular modulator that decreases diastolic blood pressure and pronounces increases in myocardial contractility. Ro 363 is an effective and highly selective β1-adrenoceptor agonist.
CAS:
74513-77-2
Formula:
C19H25NO6
Molecular Weight:
363.4
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.98
SMILES:
OC1=CC=C(C=C1O)OCC(CNCCC2=CC=C(C(OC)=C2)OC)O
Target:
Adrenergic Receptor

References

1. Maccarrone C, et al. Comparison of the Arrhythmogenic Actions of (-)-Isoprenaline, Dobutamine and the selective beta 1-adrenoceptor agonist, (+/-)-(1-[3',4'-dihydroxyphenoxy] -2-hydroxy-[3",4"-dimethoxy phenethylamino]-propane)-oxalate (Ro 363). Arzneimittelforschung. 1985;35(3):592-8. 2. Iakovidis D, et al. In vitro activity of RO363, a beta1-adrenoceptor selective agonist. Br J Pharmacol. 1980 Apr;68(4):677-85. 3. Einstein R, et al. Comparison of the cardiac effects of beta-adrenoreceptor agonists in anaesthetised and conscious dogs. J Auton Pharmacol. 1986 Mar;6(1):9-14.