TargetMol

MSN-125

Product Code:
 
TAR-T16155
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16155-5mg5mg£704.00
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Quantity:
TAR-T16155-50mg50mg£1,661.00
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Quantity:
TAR-T16155-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MSN-125 effectively inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons protect primary neurons against glutamate excitotoxicity. MSN-125 is an effective Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) (IC50: 4 μM).
CAS:
1592908-16-1
Formula:
C36H38BrN3O6
Molecular Weight:
688.619
Pathway:
Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
COCCOCOc1ccc2[C@@H]([C@@H](CN)Oc2c1)N(Cc1ccc(Br)cc1)C(=O)[C@H](Cc1ccccc1)NC(=O)c1ccccc1
Target:
Akt

References

1. Niu X, et al. A Small-Molecule Inhibitor of Bax and Bak Oligomerization Prevents Genotoxic Cell Death and Promotes Neuroprotection. Cell?Chem Biol. 2017 Apr 20;24(4):493-506.e5.