TargetMol

MRS1177

Product Code:
 
TAR-T16137
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16137-5mg5mg£850.00
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TAR-T16137-50mg50mg£1,661.00
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Quantity:
TAR-T16137-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).
CAS:
183721-13-3
Formula:
C20H12ClN5O2
Molecular Weight:
389.8
Pathway:
Proteases/Proteasome
Purity:
0.98
SMILES:
Clc1ccc2nc(NC(=O)c3ccccc3)n3nc(nc3c2c1)-c1ccco1
Target:
MMP

References

1. Tafi A, et al. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models. J Med Chem. 2006 Jul 13;49(14):4085-97. 2. Cheong SL, et al. Pharmacophore elucidation for a new series of 2-aryl-pyrazolo-triazolo-pyrimidines as potent human A3 adenosine receptor antagonists. Bioorg Med Chem Lett. 2011 May 15;21(10):2898-905.