TargetMol

MLT-747

Product Code:
 
TAR-T16119
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T16119-5mg5mg£304.00
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Quantity:
TAR-T16119-50mg50mg£1,267.00
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Quantity:
TAR-T16119-100mg100mg£1,966.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
MLT-747 is an effective and allosteric inhibitor of MALT1. It binds MALT1 in the allosteric Trp580 pocket (IC50: 14 nM).
CAS:
2097853-86-4
Formula:
C20H21Cl2N7O3
Molecular Weight:
478.33
Purity:
0.98
SMILES:
CO[C@@H](C)c1c(NC(=O)Nc2cnc(C(=O)N3CCCC3)c(Cl)c2)cnc2cc(Cl)nn12

References

1. Quancard J, et al. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient. Nat Chem Biol. 2019 Mar;15(3):304-313.