TargetMol

ML753286

Product Code:
 
TAR-T16113
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16113-5mg5mg£704.00
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TAR-T16113-50mg50mg£1,661.00
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Quantity:
TAR-T16113-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions. ML753286 is an orally active and selective inhibitor of BCRP (IC50: 0.6 μM). It is also stable in plasma across species.
CAS:
1699720-89-2
Formula:
C20H25N3O3
Molecular Weight:
355.438
Pathway:
Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
[H][C@]12Cc3c([nH]c4cc(OC)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](C)NC2=O
Target:
AMPK

References

1. Liao M, et al. Preclinical absorption, distribution, metabolism, excretion and pharmacokinetics of a novelselective inhibitor of breast cancer resistance protein (BCRP). Xenobiotica. 2018 May;48(5):467-477.