TargetMol

GNE-0723

Product Code:
 
TAR-T15407
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15407-5mg5mg£1,171.00
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TAR-T15407-50mg50mg£2,303.00
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TAR-T15407-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
GNE 0723 is an NMDAR brain permeable positive allosteric modulator (EC50: 21 nM for GluN2A; 7.4 and 6.2 μM for GluN2C and GluN2D, respectively).
CAS:
1883518-31-7
Formula:
C16H8ClF6N5OS
Molecular Weight:
467.77
Purity:
0.98
SMILES:
FC(F)(F)c1cc(Cl)n(Cc2cc(=O)n3c([C@@H]4C[C@H]4C#N)c(sc3n2)C(F)(F)F)n1

References

1. Villemure E, et al. GluN2A-Selective Pyridopyrimidinone Series of NMDAR Positive Allosteric Modulators with an Improved in Vivo Profile. ACS Med Chem Lett. 2016 Oct 31;8(1):84-89.