TargetMol

E-5324

Product Code:
 
TAR-T15187
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15187-5mg5mg£1,091.00
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TAR-T15187-50mg50mg£2,143.00
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Quantity:
TAR-T15187-100mg100mg£2,801.00
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This product comes from: United States.
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Further Information

Bioactivity:
E-5324 is potent cholesterol acyltransferase (ACAT) inhibitor (IC50s: 44 to 190 nM).
CAS:
141799-76-0
Formula:
C26H34N4O2
Molecular Weight:
434.584
Purity:
0.98
SMILES:
CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(c1CC)-c1ccccc1

References

1. Kogushi M, et al. Effect of E5324, a novel inhibitor of acyl-CoA:cholesterol acyltransferase, on cholesteryl ester synthesis and accumulation in macrophages. Jpn J Pharmacol. 1995 Jun;68(2):191-9. 2. Kogushi M, et al. Anti-atherosclerotic effect of E5324, an inhibitor of acyl-CoA:cholesterol acyltransferase, in Watanabe heritable hyperlipidemic rabbits. Atherosclerosis. 1996 Aug 2;124(2):203-10.