TargetMol

Cbz-B3A

Product Code:
 
TAR-T14886
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T14886-5mg5mg£850.00
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Quantity:
TAR-T14886-50mg50mg£1,661.00
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Quantity:
TAR-T14886-100mg100mg£2,079.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appears to bind to ubiquitin 1, 2, and 4. It inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).
CAS:
1884710-81-9
Formula:
C35H58N6O9
Molecular Weight:
706.882
Purity:
0.98
SMILES:
CC(C)(C)OC(=O)N[C@@H](CCCN=C(NC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C)C(=O)NCCCCCCNC(=O)OCc1ccccc1

References

1. Coffey RT, et al. Ubiquilin-mediated Small Molecule Inhibition of Mammalian Target of Rapamycin Complex 1 (mTORC1) Signaling. J Biol Chem. 2016 Mar 4;291(10):5221-33.