TargetMol

Cabergoline

Product Code:
 
TAR-T14853
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14853-1mg1mg£98.00
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TAR-T14853-5mg5mg£132.00
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TAR-T14853-1mL1 mL * 10 mM (in DMSO)£139.00
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TAR-T14853-10mg10mg£168.00
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TAR-T14853-25mg25mg£266.00
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TAR-T14853-50mg50mg£431.00
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Quantity:
TAR-T14853-100mg100mg£600.00
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Further Information

Bioactivity:
Cabergoline is an ergot derived-dopamine D2-like receptor agonist. It has high affinity for D2, D3, and 5-HT2B receptors (Ki=0.7, 1.5, and 1.2, respectively).Cabergoline permits rapid and effective hormonal and tumor control by normalizing prolactin-producing pituitary adenomas levels.
CAS:
81409-90-7
Formula:
C26H37N5O2
Molecular Weight:
451.615
Pathway:
Autophagy; GPCR/G Protein; Neuroscience
Purity:
0.9992
SMILES:
[H][C@@]12Cc3c[nH]c4cccc(c34)[C@@]1([H])C[C@H](CN2CC=C)C(=O)N(CCCN(C)C)C(=O)NCC
Target:
Dopamine Receptor; 5-HT Receptor; Autophagy

References

1. Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271. 2. Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.