TargetMol

BMT-090605

Product Code:
 
TAR-T14691
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14691-5mg5mg£1,171.00
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TAR-T14691-50mg50mg£2,303.00
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Quantity:
TAR-T14691-100mg100mg£3,042.00
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This product comes from: United States.
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Further Information

Bioactivity:
BMT-090605 is a potent, selective AAK1 inhibitor, with an IC50 of 0.6 nM. BMT-090605 inhibits BMP-2-inducible protein kinase (BIKE) and Cyclin G-associated kinase (GAK) with IC50s of 45 and 60 nM, respectively[1]. BMT-090605 shows antinociceptive activity.
CAS:
1551403-51-0
Formula:
C21H24N4O2
Molecular Weight:
364.449
Purity:
0.98
SMILES:
CC(C)C[C@H](N)COc1cc2n(C)c(=O)c3c(C)nccc3c2cc1C#N

References

1. Kostich W, et al. Inhibition of AAK1 Kinase as a Novel Therapeutic Approach to Treat Neuropathic Pain. J Pharmacol Exp Ther. 2016 Sep;358(3):371-86.