TargetMol

Biricodar

Product Code:
 
TAR-T14616
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14616-5mg5mg£1,010.00
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TAR-T14616-50mg50mg£1,982.00
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Quantity:
TAR-T14616-100mg100mg£2,560.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Biricodar is a P-glycoprotein and MRP-1 modulator.
CAS:
159997-94-1
Formula:
C34H41N3O7
Molecular Weight:
603.716
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1OC)C(=O)C(=O)N1CCCC[C@H]1C(=O)OC(CCCc1cccnc1)CCCc1cccnc1

References

1. Minderman H, et al. VX-710 (biricodar) increases drug retention and enhances chemosensitivity in resistant cells overexpressing P-glycoprotein, multidrug resistance protein, and breast cancer resistance protein. Clin Cancer Res. 2004 Mar 1;10(5):1826-34. 2. Yanagisawa T, et al. BIRICODAR (VX-710; Incel): an effective chemosensitizer in neuroblastoma. Br J Cancer. 1999 Jun;80(8):1190-6. 3. Germann UA, et al. Cellular and biochemical characterization of VX-710 as a chemosensitizer: reversal of P-glycoprotein-mediated multidrug resistance in vitro. Anticancer Drugs. 1997 Feb;8(2):125-40.