TargetMol

BI-0252

Product Code:
 
TAR-T14554
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14554-5mg5mg£1,010.00
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TAR-T14554-50mg50mg£1,982.00
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Quantity:
TAR-T14554-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis.
CAS:
1818291-27-8
Formula:
C30H26Cl2FN3O3
Molecular Weight:
566.45
Purity:
0.98
SMILES:
OC(=O)c1ccc(cc1)[C@H]1C[C@H]2[C@@H](N1)[C@H](c1cccc(Cl)c1F)[C@@]1(N2CC2CC2)C(=O)Nc2cc(Cl)ccc12

References

1. Gollner A, et al. Discovery of Novel Spiro[