TargetMol

Azt-pmap

Product Code:
 
TAR-T14488
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T14488-5mg5mg£1,010.00
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TAR-T14488-50mg50mg£1,982.00
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TAR-T14488-100mg100mg£2,560.00
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This product comes from: United States.
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Further Information

Bioactivity:
Azt-pmap shows anti-HIV activity[1]. Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2].
CAS:
142629-81-0
Formula:
C20H25N6O8P
Molecular Weight:
508.428
Pathway:
Microbiology/Virology; Proteases/Proteasome
Purity:
0.98
SMILES:
COC(=O)[C@H](C)NP(=O)(OC[C@H]1O[C@H](C[C@@H]1N=[N+]=[N-])n1cc(C)c(=O)[nH]c1=O)Oc1ccccc1
Target:
HIV Protease

References

1. McGuigan C, et al. Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT. Antiviral Res. 1992 Apr;17(4):311-21. 2. Gray LR, et al. The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes. PLoS One. 2013 Apr 16;8(4):e62196.