TargetMol

AZD 9272

Product Code:
 
TAR-T14389
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14389-1mg1mg£142.00
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TAR-T14389-5mg5mg£225.00
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TAR-T14389-10mg10mg£309.00
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TAR-T14389-25mg25mg£549.00
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TAR-T14389-50mg50mg£752.00
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TAR-T14389-100mg100mg£1,010.00
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Quantity:
TAR-T14389-500mg500mg£1,958.00
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Further Information

Bioactivity:
AZD 9272 is a antagonist of brain penetrant mGluR5.
CAS:
327056-26-8
Formula:
C14H6F2N4O
Molecular Weight:
284.226
Pathway:
Neuroscience
Purity:
0.98
SMILES:
Fc1ccc(nc1)-c1noc(n1)-c1cc(F)cc(c1)C#N
Target:
GluR

References

1. Swedberg MD, et al. AZD9272 and AZD2066: selective and highly central nervous system penetrant mGluR5 antagonists characterized by their discriminative effects. J Pharmacol Exp Ther. 2014 Aug;350(2):212-22. 2. Raboisson P, et al. Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6974-9.