TargetMol

AVE-8134

Product Code:
 
TAR-T14356
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14356-5mg5mg£850.00
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TAR-T14356-50mg50mg£1,661.00
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Quantity:
TAR-T14356-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.
CAS:
304025-09-0
Formula:
C22H23NO5
Molecular Weight:
381.428
Pathway:
DNA Damage/DNA Repair; Metabolism
Purity:
0.98
SMILES:
Cc1cccc(COCCCOCc2coc(n2)-c2ccccc2)c1C(O)=O
Target:
PPAR

References

1. Schafer HL, et al. AVE8134, a novel potent PPAR? agonist, improves lipid profile and glucose metabolism in dyslipidemic mice and type 2 diabetic rats. Acta Pharmacol Sin. 2012 Jan;33(1):82-90. 2. Linz W, et al. The peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats. Acta Pharmacol Sin. 2009 Jul;30(7):935-46.