TargetMol

Auxinole

Product Code:
 
TAR-T14353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14353-1mg1mg£98.00
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TAR-T14353-5mg5mg£131.00
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TAR-T14353-1mL1 mL * 10 mM (in DMSO)£140.00
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TAR-T14353-10mg10mg£157.00
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TAR-T14353-25mg25mg£214.00
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TAR-T14353-50mg50mg£283.00
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TAR-T14353-100mg100mg£389.00
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TAR-T14353-500mg500mg£830.00
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Further Information

Bioactivity:
Auxinole is a potent auxin antagonist of TIR1/AFB receptors, binding TIR1 to block the formation of the TIR1-IAA-Aux/IAA complex . It inhibits auxin-responsive gene expression.
CAS:
86445-22-9
Formula:
C20H19NO3
Molecular Weight:
321.376
Purity:
0.9893
SMILES:
Cc1ccc(C(=O)CC(C(O)=O)c2c[nH]c3ccccc23)c(C)c1

References

1. Hayashi K, et al. Rational design of an auxin antagonist of the SCF(TIR1) auxin receptor complex. ACS Chem Biol. 2012 Mar 16;7(3):590-8. 2. Dindas J, et al. AUX1-mediated root hair auxin influx governs SCFTIR1/AFB-type Ca2+ signaling. Nat Commun. 2018 Mar 21;9(1):1174.