TargetMol

Aplaviroc

Product Code:
 
TAR-T14307
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14307-5mg5mg£1,332.00
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Quantity:
TAR-T14307-50mg50mg£2,625.00
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Quantity:
TAR-T14307-100mg100mg£3,524.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Aplaviroc (AK 602), a SDP derivative, is a CCR5 antagonist. With IC50s of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL and HIV-1MOKW.
CAS:
461443-59-4
Formula:
C33H43N3O6
Molecular Weight:
577.722
Pathway:
Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
Purity:
0.98
SMILES:
CCCCN1C(=O)[C@H](NC(=O)C11CCN(Cc2ccc(Oc3ccc(cc3)C(O)=O)cc2)CC1)[C@H](O)C1CCCCC1
Target:
HIV Protease; CCR

References

1. Maeda K, et al. Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokine/CCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro. J Virol. 2004 Aug;78(16):8654-62.