TargetMol

Aminaftone

Product Code:
 
TAR-T14219
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14219-5mg5mg£850.00
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TAR-T14219-50mg50mg£1,661.00
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Quantity:
TAR-T14219-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aminaftone downregulates endothelin-1 (ET-1) production in vitro by interfering with the transcription of the pre-pro-ET-1 gene.
CAS:
14748-94-8
Formula:
C18H15NO4
Molecular Weight:
309.321
Purity:
0.98
SMILES:
Cc1c(O)c2ccccc2c(O)c1OC(=O)c1ccc(N)cc1

References

1. Scorza R, et al. Aminaftone, a derivative of 4-aminobenzoic acid, downregulates endothelin-1 production in ECV304 Cells: an in vitro Study. Drugs R D. 2008;9(4):251-7. 2. Zambelli V, et al. Efficacy of aminaftone in a rat model of monocrotaline-induced pulmonary hypertension. Eur J Pharmacol. 2011 Sep 30;667(1-3):287-91.