TargetMol

Cefditoren sodium

Product Code:
 
TAR-T1405L
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T1405L-5mg5mg£137.00
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Further Information

Bioactivity:
Cefditoren sodium is a cephalosporin antibiotic potentially for the treatment of bacterial infection. The expression levels of Mrp2, Bcrp, Oat2 mRNA were markedly increased, while P-gp and Oct1 mRNA were decreased. In concordance with RT-PCR results, Mrp2 expression level increased by Western blotting.
CAS:
104146-53-4
Formula:
C19H17N6NaO5S3
Molecular Weight:
528.55
Purity:
0.98
SMILES:
[Na+].CON=C(C(=O)NC1C2SCC(C=C/c3scnc3C)=C(N2C1=O)C([O-])=O)c1csc(N)n1

References

1. Sadahira T, Wada K, Araki M, Ishii A, Takamoto A, Kobayashi Y, Watanabe M, Watanabe T, Nasu Y, Kumon H; Okayama Urological Research Group (OURG).. Efficacy and safety of 3 day versus 7 day cefditoren pivoxil regimens for acute uncomplicated cystitis: multicentre, randomized, open-label trial. J Antimicrob Chemother. 2017 Feb;72(2):529-534. doi: 10.1093/jac/dkw424. PubMed PMID: 27733519. 2. Ulloa C, Guevara S, Soley C, Abdelnour A, Arguedas A. In vitro Activity of Cefditoren against Middle Ear Fluid Isolates from Costa Rican Children with Otitis Media. Chemotherapy. 2014;60(4):211-8. doi: 10.1159/000371836. PubMed PMID: 25871785. 3. Di Marco F, Braido F, Santus P, Scichilone N, Blasi F. The role of cefditoren in the treatment of lower community-acquired respiratory tract infections (LRTIs): from bacterial eradication to reduced lung inflammation and epithelial damage. Eur Rev Med Pharmacol Sci. 2014;18(3):321-32. Review. PubMed PMID: 24563430. 4. Gawande VT, Bothara KG, Singh A, Mahajan AA. Identification and Characterization of Hydrolytic Degradation Products of Cefditoren Pivoxil using LC and LC-MS/TOF. Indian J Pharm Sci. 2015 Jan-Feb;77(1):75-82. PubMed PMID: 25767321; PubMed Central PMCID: PMC4355885.