TargetMol

3CAI

Product Code:
 
TAR-T14034
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T14034-5mg5mg£111.00
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Quantity:
TAR-T14034-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T14034-10mg10mg£127.00
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TAR-T14034-25mg25mg£173.00
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TAR-T14034-50mg50mg£257.00
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Quantity:
TAR-T14034-100mg100mg£350.00
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Quantity:
TAR-T14034-200mg200mg£481.00
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Quantity:
TAR-T14034-500mg500mg£736.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
3CAI is a potent and specific AKT1 and AKT2 inhibitor which showed significant inhibition of AKT in an in vitro kinase assay and suppressed expression of AKT direct downstream targets such as mTOR and GSK3β as well as induced growth inhibition and apoptosis in colon cancer cells.
CAS:
28755-03-5
Formula:
C10H8ClNO
Molecular Weight:
193.63
Pathway:
Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
ClCC(=O)c1c[nH]c2ccccc12
Target:
Akt

References

1. Kim DJ, et al. (3-Chloroacetyl)-indole, a novel allosteric AKT inhibitor, suppresses colon cancer growth in vitro and in vivo. Cancer Prev Res (Phila). 2011 Nov;4(11):1842-51.