TargetMol

MZP-55

Product Code:
 
TAR-T13786
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13786-100mg100mgEnquire
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TAR-T13786-50mg50mgEnquire
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TAR-T13786-5mg5mg£437.00
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TAR-T13786-1mL1 mL * 10 mM (in DMSO)£470.00
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TAR-T13786-10mg10mg£631.00
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TAR-T13786-25mg25mg£1,131.00
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This product comes from: United States.
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Further Information

Bioactivity:
MZP-55 is a selective BRD3/4 degrader based on PROTAC technology(Brd4BD2 with Kd of 8 nM)
CAS:
2010159-48-3
Formula:
C57H70ClN7O10S
Molecular Weight:
1080.72
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC(N=CS1)=C1C2=CC=C(CNC([C@@H]3C[C@@H](O)CN3C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCNC(C(C=C4)=CC=C4C5=CC6=C(C=C5)N(C(C)=O)[C@@H](C)C[C@H]6NC7=CC=C(Cl)C=C7)=O)=O)=O)=O)C=C2
Target:
Epigenetic Reader Domain

References

1. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.