TargetMol

CP-10

Product Code:
 
TAR-T13627
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13627-100mg100mgEnquire
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TAR-T13627-200mg200mgEnquire
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TAR-T13627-5mg5mg£655.00
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TAR-T13627-10mg10mg£870.00
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TAR-T13627-1mL1 mL * 10 mM (in DMSO)£919.00
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TAR-T13627-50mg50mg£1,830.00
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This product comes from: United States.
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Further Information

Bioactivity:
CP-10 is a PROTAC with highly selective and remarkable CDK6 degradation (DC50: 2.1 nM). It inhibits the proliferation of several hematopoietic cancer cells including multiple myeloma and can degrade mutated and overexpressed CDK6.
CAS:
2366268-80-4
Formula:
C44H49N13O7
Molecular Weight:
871.96
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
CC(=O)c1c(C)c2cnc(Nc3ccc(cn3)N3CCN(Cc4cn(CCOCCNc5cccc6C(=O)N(C7CCC(=O)NC7=O)C(=O)c56)nn4)CC3)nc2n(C2CCCC2)c1=O
Target:
CDK

References

1. Su S, et al. Potent and Preferential Degradation of CDK6 via Proteolysis Targeting Chimera Degraders. J Med Chem. 2019 Aug 2.