TargetMol

TP-472

Product Code:
 
TAR-T13190
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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Further Information

Bioactivity:
TP-472 is a selective inhibitor of BRD9 (Kd: 33 nM).
CAS:
2079895-62-6
Formula:
C20H19N3O2
Molecular Weight:
333.391
Pathway:
Chromatin/Epigenetic
Purity:
0.98
SMILES:
CC(=O)c1cc(-c2cc(ccc2C)C(=O)NC2CC2)c2ncccn12
Target:
Epigenetic Reader Domain

References

1. Moustakim M, et al. Chemical probes and inhibitors of bromodomains outside the BET family. Medchemcomm. 2016 Dec 7;7(12):2246-2264. 2. Gatchalian J, et al. A non-canonical BRD9-containing BAF chromatin remodeling complex regulates naive pluripotency in mouse embryonic stem cells. Nat Commun. 2018 Dec 3;9(1):5139.