TargetMol

SGL5213

Product Code:
 
TAR-T12892
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12892-5mg5mg£1,412.00
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TAR-T12892-50mg50mg£2,785.00
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Quantity:
TAR-T12892-100mg100mg£3,765.00
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This product comes from: United States.
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Further Information

Bioactivity:
SGL5213 is an oral active and low-absorbable inhibitor of sodium-dependent glucose cotransporter 1 (SGLT1)(hSGLT1 and hSGLT2 with IC50 values of 29 nM and 20 nM , respectively),and has potential to treat type 2 diabetes.
CAS:
1240305-17-2
Formula:
C37H55N3O8
Molecular Weight:
669.86
Pathway:
GPCR/G Protein
Purity:
0.98
SMILES:
COc1cc(C(C)C)c(Cc2ccc(C=CC(C)(C)C(=O)NC(C)(C)C(=O)NCCN(C)C)cc2)cc1[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Target:
SGLT

References

1. Kuroda S, et al. Discovery of potent, low-absorbable sodium-dependent glucose cotransporter 1 (SGLT1) inhibitor SGL5213 for type 2 diabetes treatment. Bioorg Med Chem. 2019 Jan 15;27(2):394-409.