TargetMol

S119-8

Product Code:
 
TAR-T12818
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12818-5mg5mg£122.00
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Quantity:
TAR-T12818-1mL1 mL * 10 mM (in DMSO)£127.00
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Quantity:
TAR-T12818-10mg10mg£161.00
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Quantity:
TAR-T12818-25mg25mg£269.00
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Quantity:
TAR-T12818-50mg50mg£436.00
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Quantity:
TAR-T12818-100mg100mg£610.00
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Quantity:
TAR-T12818-500mg500mg£1,219.00
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This product comes from: United States.
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Further Information

Bioactivity:
RN-18 antagonizes Vif function and inhibits HIV-1 replication only in the presence of A3G. RN-18 increases cellular A3G levels in a Vif-dependent manner and increases A3G incorporation into virions without inhibiting general proteasome-mediated protein degradation. RN-18 enhances Vif degradation only in the presence of A3G, reduces viral infectivity by increasing A3G incorporation into virions and enhances cytidine deamination of the viral genome.
CAS:
443639-96-1
Formula:
C23H24N2O
Molecular Weight:
344.45
Pathway:
Microbiology/Virology
Purity:
0.9983
SMILES:
CC(C)(C)c1ccc(cc1)C(=O)Nc1ccc(Nc2ccccc2)cc1
Target:
Influenza Virus

References

1. White KM, et al. Broad Spectrum Inhibitor of Influenza A and B Viruses Targeting the Viral Nucleoprotein. ACS Infect Dis. 2018 Feb 9;4(2):146-157.