TargetMol

ROR agonist-1

Product Code:
 
TAR-T12750
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12750-5mg5mg£850.00
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Quantity:
TAR-T12750-50mg50mg£1,661.00
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Quantity:
TAR-T12750-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
ROR agonist-1 is a potent and orally bioavailable the retinoic acid receptor-related orphan receptor C2 (RORC2) inverse agonist(inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5).
CAS:
2361528-74-5
Formula:
C21H20F6N2O5S
Molecular Weight:
526.45
Purity:
0.98
SMILES:
CCS(=O)(=O)c1ccc(cc1)[C@@H](NC(C)=O)C(=O)Nc1ccc(cc1)C(O)(C(F)(F)F)C(F)(F)F

References

1. von Berg S, et al. Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2. ACS Med Chem Lett. 2019 May 29;10(6):972-977.