TargetMol

PI3K α/mTOR-IN-1

Product Code:
 
TAR-T12589
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12589-1mg1mg£597.00
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Quantity:
TAR-T12589-5mg5mg£1,107.00
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Quantity:
TAR-T12589-10mg10mg£1,846.00
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Quantity:
TAR-T12589-25mg25mg£3,010.00
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Quantity:
TAR-T12589-50mg50mg£4,480.00
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Quantity:
TAR-T12589-100mg100mg£6,681.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
PI3Kα/mTOR-IN-1 is a potent dual inhibitor PI3Kα/mTOR(an IC50 of 7 nM for PI3Kα in a cell assay, and Kis of 10.6 nM and 12.5 nM for mTOR and PI3Kα in a cell free assay , respectively )
CAS:
1013098-90-2
Formula:
C16H18N6O
Molecular Weight:
310.361
Pathway:
PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
Cc1nc(N)nc2n(C3CCCC3)c(=O)c(cc12)-c1cn[nH]c1
Target:
PI3K

References

1. Le PT, et al. Design and synthesis of a novel pyrrolidinyl pyrido pyrimidinone derivative as a potent inhibitor of PI3K? and mTOR. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5098-103.