TargetMol

Paprotrain

Product Code:
 
TAR-T12359
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12359-5mg5mg£108.00
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TAR-T12359-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T12359-10mg10mg£124.00
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TAR-T12359-25mg25mg£164.00
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TAR-T12359-50mg50mg£221.00
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TAR-T12359-100mg100mg£341.00
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TAR-T12359-200mg200mg£466.00
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TAR-T12359-500mg500mg£702.00
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This product comes from: United States.
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Further Information

Bioactivity:
Paprotrain inhibits the ATPase activity of MKLP-2 with an IC50 of 1.35 μM and a Ki of 3.36 μM.
CAS:
57046-73-8
Formula:
C16H11N3
Molecular Weight:
245.285
Pathway:
Cytoskeletal Signaling
Purity:
0.9969
SMILES:
N#CC(=C/c1cccnc1)c1c[nH]c2ccccc12
Target:
Kinesin

References

1. Labri?re C, et al. Further investigation of Paprotrain:Towards the conception of selective and multi-targeted CNS kinase inhibitors. Eur J Med Chem. 2016 Nov 29;124:920-934. 2. Liu J, et al. MKlp2 inhibitor paprotrain affects polar body extrusion during mouse oocyte maturation. Reprod Biol Endocrinol. 2013 Dec 21;11:117. 3. Zhang Y, et al. KIF20A regulates porcine oocyte maturation and early embryo development. 4. Tcherniuk S, et al. Relocation of Aurora?B and survivin from centromeres to the central spindle impaired by a kinesin-specific MKLP-2 inhibitor. Angew Chem Int Ed Engl. 2010 Oct 25;49(44):8228-31.