TargetMol

Monomethyl fumarate

Product Code:
 
TAR-T12095
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T12095-500mg500mg£104.00
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Quantity:
TAR-T12095-1mL1 mL * 10 mM (in DMSO)£107.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Monomethyl fumarate is a potent agonist of GPR109A .
CAS:
2756-87-8
Formula:
C5H6O4
Molecular Weight:
130.099
Pathway:
Endocrinology/Hormones; Metabolism; GPCR/G Protein
Purity:
0.98
SMILES:
COC(=O)C=CC(O)=O
Target:
GPR; Drug Metabolite

References

1. Tang H, et al. The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. Biochem Biophys Res Commun. 2008 Oct 31;375(4):562-5. 2. Jiang D, et al. Monomethyl Fumarate Protects the Retina From Light-Induced Retinopathy. Invest Ophthalmol Vis Sci. 2019 Mar 1;60(4):1275-1285. 3. Sghaier R, et al. Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrialalterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7?-hydroxycholesterol. J Steroid Biochem Mol Biol. 2019 Nov;194:105432.